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Hepatitis C Viral RNA : Detection Through PCR

Hepatitis C is a liver infection caused by the hepatitis C virus (HCV). Hepatitis C is spread through contact with blood from an infected person, by sharing needles or other equipment used to prepare and inject drugs.

KEY FACTS :

  1. For more than half of people who become infected with the HCV, it becomes a long-term, chronic infection. Globally, an estimated 58 million people have chronic HCV infection, with about 1.5 million new infections occurring per year.

  2. Chronic hepatitis C can result in serious, even life-threatening health problems like cirrhosis and liver cancer. Symptoms often appear in advanced liver disease.

  3. In 2019, WHO estimated that approximately 290 000 people died from hepatitis C, mostly from cirrhosis and hepatocellular carcinoma (primary liver cancer).

  4. There is no vaccine for Hepatitis C.

  5. Getting tested for hepatitis C is important, because newer therapy can cure most people with hepatitis C in 8 to 12 weeks.

 

HCV RNA Quantitative PCR At Sampurna Sodani Diagnostic Clinic :
Real-Time Quantitative Polymerase Chain Reaction (PCR) test for the detection of Hepatitis C Virus RNA in human serum or plasma, encompassing six genotypes (HCV-1A, TM 2B, 3, 4, 5 & 6).

  • Sensitivity & limit of detection : 227.32 IU/ml.

  • TAT : Same day

  • Sample type : Serum/ plasma

PURPOSE :
1. Direct Detection and quantification of hepatitis C virus (HCV) RNA in serum/plasma of infected patients.
2. Chronic HCV infection can be confirmed by PCR as anti-HCV antibodies may appear despite clearing spontaneously the infection by about 30% of the infected population with a strong immune response and without any treatment.
3. Successful treatment decreases the risk of hepatocellular carcinoma by almost 75%. Getting tested for hepatitis C is important, because treatments can cure most people with hepatitis C in 8 to 12 weeks.

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